Nutrition and HIV/AIDS: Evidence, Gaps, and Priority Actions

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چکیده

In Africa, where more than 25 million people are living with HIV/AIDS, malnutrition and food insecurity are endemic. Today, nearly 40% of African children < 5 years old are stunted due to chronic nutritional deprivation. Underweight, an indicator of chronic and acute malnutrition, was the leading cause of mortality worldwide, responsible for 3.7 million deaths in 2000. Nearly half of these deaths (48.6%) occurred in sub-Saharan Africa. The effects of malnutrition on the immune system are well known and include decreases in CD4 Tcells, suppression of delayed hypersensitivity, and abnormal B-cell responses. The immune suppression caused by protein-energy malnutrition is similar in many ways to the effects of HIV infection. This document summarizes the evidence, gaps, and priority actions related to nutrition and HIV/AIDS.

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تاریخ انتشار 2004